CHD1 抗体 (C-Term)
Quick Overview for CHD1 抗体 (C-Term) (ABIN6971529)
抗原
See all CHD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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产品特性
- CHD1 (Chromo-ATPase/Helicase-DNA-binding protein 1 ) is a member of the CHD family of ATP-dependent chromatin remodeling factors implicated in RNA polymerase II transcriptional regulation. They are characterized by the presence of a double chromodomains (Chromatin Organization Modifier) and SNF2-related helicase/ATPase domains. The CHD1/CHD2 sub-family of CHD proteins also contain a C-terminal DNA binding domain that recognizes AT-rich sequences. CHD proteins alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD1 has been shown to interact with histone H3 trimethylated at lysine 4 (H3K4Me3) and also is required for the maintenance of stem cell pluripotency. CHD1 antibody (mAb) (Clone 2F11) was raised in a Rat host. It has been validated for use in Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
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纯化方法
- Protein G Chromatography
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免疫原
- This CHD1 antibody was raised against a peptide corresponding to the C-terminus of mouse CHD1.
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亚型
- IgG2a
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anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (C-Term) antibody
CHD1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1501-1710) antibodyCHD1 适用: 人 ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (C-Term) antibodyCHD1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) antibodyCHD1 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1331-1380) antibodyCHD1 适用: 人, 小鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 251-467) antibodyCHD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))
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别名
- CHD1
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分子量
- 210 kDa
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NCBI登录号
- NP_031716
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途径
- Chromatin Binding
抗原
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