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CHD1 抗体 (C-Term)

This 大鼠 单克隆 anti-CHD1 antibody (Clone 2F11) specifically detects CHD1 in WB, IF 和 ICC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6971529
发货至: 中国
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Quick Overview for CHD1 抗体 (C-Term) (ABIN6971529)

抗原

See all CHD1 抗体
CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

适用

  • 26
  • 10
  • 3
  • 3
  • 3
  • 2
  • 1
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  • 1
人, 小鼠

宿主

  • 20
  • 5
  • 3
  • 1
大鼠

克隆类型

  • 25
  • 4
单克隆

标记

  • 29
This CHD1 antibody is un-conjugated

应用范围

  • 23
  • 15
  • 7
  • 4
  • 4
  • 3
  • 2
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  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

2F11
  • 抗原表位

    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    产品特性

    CHD1 (Chromo-ATPase/Helicase-DNA-binding protein 1 ) is a member of the CHD family of ATP-dependent chromatin remodeling factors implicated in RNA polymerase II transcriptional regulation. They are characterized by the presence of a double chromodomains (Chromatin Organization Modifier) and SNF2-related helicase/ATPase domains. The CHD1/CHD2 sub-family of CHD proteins also contain a C-terminal DNA binding domain that recognizes AT-rich sequences. CHD proteins alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD1 has been shown to interact with histone H3 trimethylated at lysine 4 (H3K4Me3) and also is required for the maintenance of stem cell pluripotency. CHD1 antibody (mAb) (Clone 2F11) was raised in a Rat host. It has been validated for use in Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.

    纯化方法

    Protein G Chromatography

    免疫原

    This CHD1 antibody was raised against a peptide corresponding to the C-terminus of mouse CHD1.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

    别名

    CHD1

    分子量

    210 kDa

    NCBI登录号

    NP_031716

    途径

    Chromatin Binding
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