PRDM1 抗体 (N-Term)
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Quick Overview for PRDM1 抗体 (N-Term) (ABIN6971445)
抗原
See all PRDM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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产品特性
- BLIMP1 / PRDM1 (Beta-interferon gene positive regulatory domain I-binding factor, PR domain-containing protein 1 Positive regulatory domain I-binding factor 1) is a DNA sequence-specific transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene, as well as other genes. It is required for maturation of B-lymphocytes into immunoglobin secreting plasma cells through direct repression of transcription factors such as Pax5, Bcl6, and Myc, which function in the lineage commitment and proliferation of B cells. BLIMP1 / PRDM1 contains an N-terminal SET domain and four C-terminal C2H2-type zinc-finger motifs. It is also required for effector T-cell function and for the specification of primordial germ cell lineages. BLIMP1 / PRDM1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunofluorescence and Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This BLIMP1 / PRDM1 antibody was raised against a peptide within the N-terminal half of human BLIMP1 / PRDM1.
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亚型
- IgG
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anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 1-109) antibody
PRDM1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (Internal Region) antibodyVerified PRDM1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 690-825) antibodyPRDM1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F1B6 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 1-109) antibodyPRDM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 422-493) antibodyPRDM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 690-825) antibodyPRDM1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 7C11H1 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (C-Term) antibodyVerified PRDM1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) antibodyPRDM1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 199-409) antibodyPRDM1 适用: 人, 小鼠, Pig WB, ELISA, IHC, IP, ICC, FACS, IF 宿主: 小鼠 Monoclonal 3H2-E8 unconjugated
anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (AA 29-149) antibodyPRDM1 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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别名
- BLIMP1 / PRDM1
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分子量
- 110 kDa
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NCBI登录号
- NP_001189
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途径
- Regulation of Muscle Cell Differentiation
抗原
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