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Androgen Receptor 抗体 (N-Term)

The 兔 多克隆 anti-Androgen Receptor antibody (ABIN6971389) specifically detects Androgen Receptor in WB, ChIP 和 ChIP-seq. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6971389
发货至: 中国
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Quick Overview for Androgen Receptor 抗体 (N-Term) (ABIN6971389)

抗原

See all Androgen Receptor (AR) 抗体
Androgen Receptor (AR)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Androgen Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
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    N-Term

    产品特性

    Androgen Receptor (AR, NR3C4) is a nuclear receptor that facilitates signaling of testosterone and other androgenic hormones in the cytoplasm and translocates into the nucleus upon hormone binding. AR serves as a DNA binding activator of transcription of hormone responsive genes. There are two forms of the Androgen Receptor, the AR-A form, lacking the N-terminal 187 amino acids and the full length AR-B form. Androgen Receptor is involved in the development of both primary and secondary male sexual characteristics and abnormal expression of AR is linked to prostate cancer. Androgen Receptor antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq and Western blot, it has been shown to react with Human and Mouse samples.

    纯化方法

    Protein A Chromatography

    免疫原

    This Androgen Receptor antibody was raised against a peptide in the N-terminal region of human Androgen receptor.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS pH 7.5 containing 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    Androgen Receptor (AR)

    别名

    Androgen Receptor

    分子量

    110 kDa

    NCBI登录号

    NP_000035

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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