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AGO2 抗体 (AA 1-148)

This 小鼠 单克隆 anti-AGO2 antibody (Clone 1B1-E2H5) specifically detects AGO2 in WB, IF, ICC 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN6971363
发货至: 中国
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Quick Overview for AGO2 抗体 (AA 1-148) (ABIN6971363)

抗原

See all AGO2 抗体
AGO2 (Argonaute 2 (AGO2))

适用

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宿主

  • 55
  • 7
小鼠

克隆类型

  • 31
  • 31
单克隆

标记

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This AGO2 antibody is un-conjugated

应用范围

  • 41
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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

克隆位点

1B1-E2H5
  • 抗原表位

    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
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    AA 1-148

    产品特性

    Argonaute 2 (Ago2, aka EIF2C2) is a member of the Argonaute family of proteins involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Binding of RISC can inhibit mRNA translation and results in the degradation of the mRNA through the action of Ago2-mediated target cleavage. Ago2 antibody (mAb) (Clone 1B1-E2H5) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunoprecipitation and Western blot, it has been shown to react with Human samples.

    纯化方法

    Protein G Chromatography

    免疫原

    This Ago2 antibody was raised against a recombinant protein corresponding to amino acids 1-148 of human Ago2.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原

    AGO2 (Argonaute 2 (AGO2))

    别名

    Ago2

    分子量

    100 kDa

    NCBI登录号

    NP_036286

    途径

    Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization
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