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IL-21 抗体 (Biotin)

This anti-IL-21 antibody is a 小鼠 单克隆 antibody detecting IL-21 in ELISA. Suitable for 人 和 Non-Human Primate. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN6964032
发货至: 中国

Quick Overview for IL-21 抗体 (Biotin) (ABIN6964032)

抗原

See all IL-21 (IL21) 抗体
IL-21 (IL21) (Interleukin 21 (IL21))

适用

  • 87
  • 32
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, Non-Human Primate

宿主

  • 79
  • 20
  • 5
  • 2
  • 1
小鼠

克隆类型

  • 85
  • 18
  • 2
单克隆

标记

  • 59
  • 10
  • 6
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IL-21 antibody is conjugated to Biotin

应用范围

  • 74
  • 50
  • 25
  • 18
  • 13
  • 12
  • 7
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  • 5
  • 4
  • 3
  • 3
  • 2
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  • 1
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ELISA

克隆位点

MT21-3m
  • 特异性

    Native and recombinant human IL-21

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Recombinant human IL-21

    亚型

    IgG1
  • 应用备注

    To retain detectable levels of IL-21 in cell culture supernatants, biotinylated mAb MT21.3m can be included during cell culture. The antibody will bind to secreted IL-21 thus preventing IL-21 from interacting with its receptor. In this way, IL-21 is kept in solution and can be quantified in ELISA. For this purpose, MT21.3m is free of preservatives. Please note that mAb MT21.3m is optimized for use with human IL-21 ELISA kits and anti-human IL-21 mAbs from Mabtech.

    说明

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS free of preservatives

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Laestadius, Ingelman-Sundberg, Myrberg, Verme, Sundberg, Schweiger, Saghafian-Hedengren, Nilsson: "Altered proportions of circulating CXCR5+ helper T cells do not dampen influenza vaccine responses in children with rheumatic disease." in: Vaccine, Vol. 37, Issue 28, pp. 3685-3693, (2020) (PubMed).

    Yamamoto, Kitawaki, Sugimoto, Fujita, Kawase, Takaori-Kondo, Kadowaki: "Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide." in: Immunology letters, Vol. 211, pp. 41-48, (2020) (PubMed).

    Lasaviciute, Björkander, Carvalho-Queiroz, Hed Myrberg, Nussbaum, Nilsson, Bemark, Nilsson, Sverremark-Ekström, Saghafian-Hedengren: "Epstein-Barr Virus, but Not Cytomegalovirus, Latency Accelerates the Decay of Childhood Measles and Rubella Vaccine Responses-A 10-Year Follow-up of a Swedish Birth Cohort." in: Frontiers in immunology, Vol. 8, pp. 1865, (2017) (PubMed).

    Amu, Lantto Graham, Bekele, Nasi, Bengtsson, Rethi, Sorial, Meini, Zazzi, Hejdeman, Chiodi: "Dysfunctional phenotypes of CD4+ and CD8+ T cells are comparable in patients initiating ART during early or chronic HIV-1 infection." in: Medicine, Vol. 95, Issue 23, pp. e3738, (2017) (PubMed).

    Huang, Ehrnfelt, Paulie, Zuber, Ahlborg: "ELISpot and ELISA analyses of human IL-21-secreting cells: Impact of blocking IL-21 interaction with cellular receptors." in: Journal of immunological methods, Vol. 417, pp. 60-66, (2015) (PubMed).

  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL21

    基因ID

    59067

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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