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Interleukin 17a 抗体

This anti-Interleukin 17a antibody is a 小鼠 单克隆 antibody detecting Interleukin 17a in Neut. Suitable for 人.
产品编号 ABIN6964028
发货至: 中国

Quick Overview for Interleukin 17a 抗体 (ABIN6964028)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Interleukin 17a antibody is un-conjugated

应用范围

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Neutralization (Neut)

克隆位点

MT504
  • 特异性

    Native and recombinant IL-17A.

    交叉反应 (详细)

    The antibody cross-reacts with IL-17A from non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot.

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Recombinant human IL-17A

    亚型

    IgG1
  • 应用备注

    Neutralization of human IL-17A bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays. Neutralization Neutralization assay: Neutralization of human IL-17A induced IL-6 production (see graph). To determine the neutralizing capacity and ND50, various concentrations of mAb MT504 and human recombinant IL-17A were added to normal human dermal fibroblasts. Following overnight incubation, cell supernatants were quantified in IL-6 ELISA. Neutralization dose 50 (ND50): MT504 neutralized the effect of IL-17A at a ND50value of 0.01-0.03 μg/mL when 10 ng/mL IL-17A was present. ND50 is defined as the concentration of antibody that results in 50 % inhibition of the biological response under the experimental conditions specified.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS free of preservatives

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

    有效期

    18 months
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL17A

    基因ID

    3605
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