Interleukin 17a 抗体
Quick Overview for Interleukin 17a 抗体 (ABIN6964028)
抗原
See all Interleukin 17a (IL17A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Native and recombinant IL-17A.
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交叉反应 (详细)
- The antibody cross-reacts with IL-17A from non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot.
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纯化方法
- Purified from in vitro cultures by protein G affinity chromatography.
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免疫原
- Recombinant human IL-17A
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亚型
- IgG1
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应用备注
- Neutralization of human IL-17A bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays. Neutralization Neutralization assay: Neutralization of human IL-17A induced IL-6 production (see graph). To determine the neutralizing capacity and ND50, various concentrations of mAb MT504 and human recombinant IL-17A were added to normal human dermal fibroblasts. Following overnight incubation, cell supernatants were quantified in IL-6 ELISA. Neutralization dose 50 (ND50): MT504 neutralized the effect of IL-17A at a ND50value of 0.01-0.03 μg/mL when 10 ng/mL IL-17A was present. ND50 is defined as the concentration of antibody that results in 50 % inhibition of the biological response under the experimental conditions specified.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- supplied at 0.5 mg/mL in PBS free of preservatives
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
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有效期
- 18 months
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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别名
- IL17A
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基因ID
- 3605
抗原
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