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IL-12/IL-23 p40 抗体

Cited in 3+ publications. This anti-IL-12/IL-23 p40 antibody is a 大鼠 单克隆 antibody detecting IL-12/IL-23 p40 in Neut. Suitable for 小鼠.
产品编号 ABIN6964022
发货至: 中国
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Quick Overview for IL-12/IL-23 p40 抗体 (ABIN6964022)

抗原

IL-12/IL-23 p40

适用

  • 5
  • 3
  • 1
小鼠

宿主

  • 5
  • 3
大鼠

克隆类型

  • 8
单克隆

标记

  • 4
  • 2
  • 1
  • 1
This IL-12/IL-23 p40 antibody is un-conjugated

应用范围

  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Neutralization (Neut)

克隆位点

C17-8
  • 特异性

    Native and recombinant p40 subunit of mouse IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Recombinant mouse IL-12 p70

    亚型

    IgG2a
  • 应用备注

    Neutralization of mouse IL-12 and IL-23 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    supplied at 1 mg/mL in PBS free of preservatives

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Prabhakara, Harro, Leid, Keegan, Prior, Shirtliff: "Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus." in: Infection and immunity, Vol. 79, Issue 12, pp. 5010-8, (2012) (PubMed).

    Lee, Hoeman, Hardaway, Guloglu, Ellis, Jain, Divekar, Tartar, Haymaker, Zaghouani: "Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity." in: The Journal of experimental medicine, Vol. 205, Issue 10, pp. 2269-80, (2008) (PubMed).

    Chackerian, Chen, Brodie, Mattson, McClanahan, Kastelein, Bowman: "Neutralization or absence of the interleukin-23 pathway does not compromise immunity to mycobacterial infection." in: Infection and immunity, Vol. 74, Issue 11, pp. 6092-9, (2006) (PubMed).

  • 抗原

    IL-12/IL-23 p40

    别名

    IL12/23 (p40)

    基因ID

    16160
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