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APOB 抗体 (Biotin)

APOB 适用: 人, Non-Human Primate WB, ELISA 宿主: 小鼠 Monoclonal LDL 11 Biotin
产品编号 ABIN6963945
发货至: 中国
  • 抗原 See all APOB 抗体
    APOB (Apolipoprotein B (APOB))
    适用
    • 90
    • 25
    • 22
    • 6
    • 2
    人, Non-Human Primate
    宿主
    • 62
    • 33
    • 15
    • 2
    • 1
    小鼠
    克隆类型
    • 78
    • 33
    单克隆
    标记
    • 47
    • 20
    • 17
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOB antibody is conjugated to Biotin
    应用范围
    • 64
    • 45
    • 33
    • 17
    • 15
    • 14
    • 10
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    Native apoB in the form of LDL.
    交叉反应 (详细)
    The monoclonal antibody cross-reacts with apoB from non-human primates.
    纯化方法
    Purified from in vitro cultures by protein G affinity chromatography.
    免疫原
    Human LDL
    克隆位点
    LDL 11
    亚型
    IgG1
    Top Product
    Discover our top product APOB Primary Antibody
  • 应用备注
    For quantification of apoB in serum/plasma samples and cell culture supernatants using ELISA. LDL 11 is recommended as detection mAb in combination with coating mAb LDL 20/17 . The antibody is also suitable for immunoprecipitation and Western blot.
    说明

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    supplied at 1 mg/mL in PBS with 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
    有效期
    18 months
  • Yu, Rimbert, Palmer, Toyohara, Xia, Xia, Ferreira, Chen, Chen, Loaiza, Horwitz, Kacergis, Zhao, Soukas, Kuivenhoven, Kathiresan, Cowan: "GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis." in: Cell, Vol. 179, Issue 6, pp. 1276-1288.e14, (2020) (PubMed).

    Cayo, Mallanna, Di Furio, Jing, Tolliver, Bures, Urick, Noto, Pashos, Greseth, Czarnecki, Traktman, Yang, Morrisey, Grompe, Rader, Duncan: "A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia." in: Cell stem cell, Vol. 20, Issue 4, pp. 478-489.e5, (2017) (PubMed).

    Vu, Bemis, Benson, Bista, Carney, Fahrner, Lee, Liu, Lonkar, Milne, Nichols, Picarella, Shoelson, Smith, Ting, Wensley, Yeager, Zimmer, Jirousek: "Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid." in: Journal of medicinal chemistry, Vol. 59, Issue 3, pp. 1217-31, (2016) (PubMed).

    Bissig-Choisat, Wang, Legras, Saha, Chen, Bell, Pankowicz, Hill, Barzi, Leyton, Leung, Kruse, Himes, Goss, Wilson, Chan, Lagor, Bissig: "Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).

    Derwall, Malhotra, Lai, Beppu, Aikawa, Seehra, Zapol, Bloch, Yu: "Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 32, Issue 3, pp. 613-22, (2012) (PubMed).

  • 抗原
    APOB (Apolipoprotein B (APOB))
    别名
    apoB (APOB 产品)
    别名
    FLDB antibody, LDLCQ4 antibody, Ac1-060 antibody, Apo B-100 antibody, ApoB-100 antibody, ApoB-48 antibody, AI315052 antibody, apob-100 antibody, apob-48 antibody, APOB-100 antibody, ApoB(100) antibody, APOB antibody, apolipoprotein B antibody, APOB antibody, Apob antibody
    基因ID
    338
    途径
    Lipid Metabolism
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