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IL-21 抗体 (Biotin)

This anti-IL-21 antibody is a 小鼠 单克隆 antibody detecting IL-21 in ELISA 和 ELISpot. Suitable for 人 和 Non-Human Primate. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN6963916
发货至: 中国

Quick Overview for IL-21 抗体 (Biotin) (ABIN6963916)

抗原

See all IL-21 (IL21) 抗体
IL-21 (IL21) (Interleukin 21 (IL21))

适用

  • 87
  • 32
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  • 2
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  • 2
  • 2
  • 1
  • 1
人, Non-Human Primate

宿主

  • 79
  • 20
  • 5
  • 2
  • 1
小鼠

克隆类型

  • 85
  • 18
  • 2
单克隆

标记

  • 59
  • 10
  • 6
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IL-21 antibody is conjugated to Biotin

应用范围

  • 74
  • 50
  • 25
  • 18
  • 13
  • 12
  • 7
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  • 4
  • 3
  • 3
  • 2
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  • 1
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  • 1
ELISA, ELISpot

克隆位点

MT21-3m
  • 特异性

    Native and recombinant human IL-21

    交叉反应 (详细)

    The monoclonal antibody cross-reacts with IL-21 from non-human primates. See the Human/NHP cross-reactivity table.

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Recombinant human IL-21

    亚型

    IgG1
  • 应用备注

    For quantification of IL-21 in solution e.g. cell culture supernatants using ELISA and for enumeration of IL-21 producing cells using ELISpot. MT21.3m is recommended as detection mAb in combination with coating mAb MT216G . The antibody is also suitable for Western blot.

    说明

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Yamamoto, Kitawaki, Sugimoto, Fujita, Kawase, Takaori-Kondo, Kadowaki: "Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide." in: Immunology letters, Vol. 211, pp. 41-48, (2020) (PubMed).

    Amu, Lantto Graham, Bekele, Nasi, Bengtsson, Rethi, Sorial, Meini, Zazzi, Hejdeman, Chiodi: "Dysfunctional phenotypes of CD4+ and CD8+ T cells are comparable in patients initiating ART during early or chronic HIV-1 infection." in: Medicine, Vol. 95, Issue 23, pp. e3738, (2017) (PubMed).

    Li, Sullivan, Rouphael, Yu, Banton, Maddur, McCausland, Chiu, Canniff, Dubey, Liu, Tran, Hagan, Duraisingham, Wieland, Mehta, Whitaker, Subramaniam, Jones, Sette, Vora, Weinberg, Mulligan, Nakaya et al.: "Metabolic Phenotypes of Response to Vaccination in Humans. ..." in: Cell, Vol. 169, Issue 5, pp. 862-877.e17, (2017) (PubMed).

    Huang, Ehrnfelt, Paulie, Zuber, Ahlborg: "ELISpot and ELISA analyses of human IL-21-secreting cells: Impact of blocking IL-21 interaction with cellular receptors." in: Journal of immunological methods, Vol. 417, pp. 60-66, (2015) (PubMed).

  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL21

    基因ID

    59067

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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