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Perforin 1 抗体 (Biotin)

This anti-Perforin 1 antibody is a 小鼠 单克隆 antibody detecting Perforin 1 in WB, ELISA, FACS, ELISpot 和 ISt. Suitable for 人, Pig 和 Non-Human Primate. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN6963874
发货至: 中国

Quick Overview for Perforin 1 抗体 (Biotin) (ABIN6963874)

抗原

See all Perforin 1 (PRF1) 抗体
Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

适用

  • 99
  • 26
  • 8
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
人, Pig, Non-Human Primate

宿主

  • 61
  • 56
  • 4
小鼠

克隆类型

  • 64
  • 57
单克隆

标记

  • 61
  • 13
  • 13
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Perforin 1 antibody is conjugated to Biotin

应用范围

  • 48
  • 47
  • 37
  • 18
  • 17
  • 13
  • 10
  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), ELISpot, Immunostaining (ISt)

克隆位点

Pf-344
  • 特异性

    Native Perforin

    交叉反应 (详细)

    The antibody also cross-reacts with Perforin from pig.

    产品特性

    This monoclonal antibody enables specific detection of human perforin in immunoassays such as ELISpot, FluoroSpot, ELISA, flow cytometry, and Western blot. Serum/Plasma samples

    纯化方法

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

    过滤

    0.2 μm filtered

    免疫原

    Native human perforin

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    ABIN6963874, ABIN7489142, ABIN6963875, ABIN6963876 and ABIN6963877 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAbs . ABIN6963874, ABIN7489142, ABIN6963875, ABIN6963876 and ABIN6963877 is also suitable for immunocytochemistry, flow cytometry and Western Blot.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    supplied at 1 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Rout: "Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157407, (2017) (PubMed).

    Kim, Saide, Farrell, Faulkner, Tailor, Ogese, Daly, Pirmohamed, Park, Naisbitt: "Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury." in: Hepatology (Baltimore, Md.), Vol. 62, Issue 3, pp. 887-99, (2015) (PubMed).

    Gudmundsdotter, Wahren, Haller, Boberg, Edbäck, Bernasconi, Buttò, Gaines, Imami, Gotch, Lori, Lisziewicz, Sandström, Hejdeman: "Amplified antigen-specific immune responses in HIV-1 infected individuals in a double blind DNA immunization and therapy interruption trial." in: Vaccine, Vol. 29, Issue 33, pp. 5558-66, (2011) (PubMed).

    Chung, Hung, Yang, Su, Huang, Wei, Chin, Chiou, Chu, Ho, Yang, Lu, Wu, Liao, Chen: "Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis." in: Nature medicine, Vol. 14, Issue 12, pp. 1343-50, (2008) (PubMed).

    Adhikary, Behrends, Moosmann, Witter, Bornkamm, Mautner: "Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins." in: The Journal of experimental medicine, Vol. 203, Issue 4, pp. 995-1006, (2006) (PubMed).

  • 抗原

    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

    别名

    Perforin

    基因ID

    5551, 396595

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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