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Perforin 1 抗体

There are 5+ publications for this product available. The 小鼠 单克隆 anti-Perforin 1 antibody is suitable to detect Perforin 1 in samples from 人 和 Non-Human Primate. It has been validated for ELISA 和 ELISpot.
产品编号 ABIN6963873
发货至: 中国
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Quick Overview for Perforin 1 抗体 (ABIN6963873)

抗原

See all Perforin 1 (PRF1) 抗体
Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

适用

  • 100
  • 30
  • 8
  • 6
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
人, Non-Human Primate

宿主

  • 62
  • 56
  • 8
小鼠

克隆类型

  • 69
  • 57
单克隆

标记

  • 59
  • 14
  • 13
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Perforin 1 antibody is un-conjugated

应用范围

  • 48
  • 43
  • 38
  • 21
  • 16
  • 11
  • 10
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, ELISpot

克隆位点

Pf-80-164
  • 特异性

    Native Perforin.

    交叉反应 (详细)

    The monoclonal antibody cross-reacts with Perforin from non-human primates.

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    免疫原

    Native human Perforin

    亚型

    IgG1
  • 应用备注

    For quantification of Perforin in solution e.g. cell culture supernatants using ELISA and for enumeration of Perforin producing cells using ELISpot. Pf-80/164 is recommended as coating mAb in combination with detection mAb Pf-344 .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    supplied at 1 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store product at 4-8°C.

    有效期

    18 months
  • Hu, Valentin, Cai, Dayton, Rosati, Ramírez-Salazar, Kulkarni, Broderick, Sardesai, Wyatt, Earl, Moss, Mullins, Pavlakis, Felber: "DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination." in: Human gene therapy, Vol. 29, Issue 9, pp. 1029-1043, (2019) (PubMed).

    Parrot, Allard, Oger, Benlalam, Raingeard de la Blétière, Coutolleau, Preisser, Desfrançois, Khammari, Dréno, Labarrière, Delneste, Guardiola, Gervois: "IL-9 promotes the survival and function of human melanoma-infiltrating CD4(+) CD8(+) double-positive T cells." in: European journal of immunology, Vol. 46, Issue 7, pp. 1770-82, (2017) (PubMed).

    Rout: "Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157407, (2017) (PubMed).

    Chung, Hung, Yang, Su, Huang, Wei, Chin, Chiou, Chu, Ho, Yang, Lu, Wu, Liao, Chen: "Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis." in: Nature medicine, Vol. 14, Issue 12, pp. 1343-50, (2008) (PubMed).

    Belyakov, Kuznetsov, Kelsall, Klinman, Moniuszko, Lemon, Markham, Pal, Clements, Lewis, Strober, Franchini, Berzofsky: "Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa." in: Blood, Vol. 107, Issue 8, pp. 3258-64, (2006) (PubMed).

  • 抗原

    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

    别名

    Perforin

    基因ID

    5551

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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