Perforin 1 抗体
Quick Overview for Perforin 1 抗体 (ABIN6963873)
抗原
See all Perforin 1 (PRF1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Native Perforin.
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交叉反应 (详细)
- The monoclonal antibody cross-reacts with Perforin from non-human primates.
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纯化方法
- Purified from in vitro cultures by protein G affinity chromatography.
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免疫原
- Native human Perforin
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亚型
- IgG1
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应用备注
- For quantification of Perforin in solution e.g. cell culture supernatants using ELISA and for enumeration of Perforin producing cells using ELISpot. Pf-80/164 is recommended as coating mAb in combination with detection mAb Pf-344 .
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- supplied at 1 mg/mL in PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store product at 4-8°C.
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有效期
- 18 months
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: "DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination." in: Human gene therapy, Vol. 29, Issue 9, pp. 1029-1043, (2019) (PubMed).
: "IL-9 promotes the survival and function of human melanoma-infiltrating CD4(+) CD8(+) double-positive T cells." in: European journal of immunology, Vol. 46, Issue 7, pp. 1770-82, (2017) (PubMed).
: "Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157407, (2017) (PubMed).
: "Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis." in: Nature medicine, Vol. 14, Issue 12, pp. 1343-50, (2008) (PubMed).
: "Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa." in: Blood, Vol. 107, Issue 8, pp. 3258-64, (2006) (PubMed).
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: "DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination." in: Human gene therapy, Vol. 29, Issue 9, pp. 1029-1043, (2019) (PubMed).
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- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
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别名
- Perforin
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基因ID
- 5551
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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