IL-12/IL-23 p40 抗体 (Biotin)
Cited in 5+ publications. This Biotin-conjugated 小鼠 单克隆 anti-IL-12/IL-23 p40 antibody (Clone MT618) specifically detects IL-12/IL-23 p40 in ELISA 和 ELISpot. The antibody is reactive with 人 和 Non-Human Primate samples.
(5 references)
产品编号 ABIN6963861
发货至:
中国
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Quick Overview for IL-12/IL-23 p40 抗体 (Biotin) (ABIN6963861)
抗原
IL-12/IL-23 p40
适用
人, Non-Human Primate
宿主
小鼠
克隆类型
单克隆
标记
This IL-12/IL-23 p40 antibody is conjugated to Biotin
应用范围
ELISA, ELISpot
克隆位点
MT618
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特异性
- Native and recombinant p40 subunit of IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).
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交叉反应 （详细）
- The monoclonal antibody cross-reacts with IL-12/-23 (p40) from non-human primates.
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产品特性
- This monoclonal antibody enables specific detection of the p40 subunit of human IL-12 and IL-23 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples
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纯化方法
- Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human IL-23
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亚型
- IgG1
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anti-IL-12/IL-23 p40 antibody (APC)
适用: 小鼠 FACS 宿主: 大鼠 Monoclonal C17-8 APC
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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ABIN6963861 and ABIN7448304 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAbs .
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
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有效期
- 18 months
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: "An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2067-2075, (2019) (PubMed).
: "The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age." in: Biogerontology, Vol. 17, Issue 1, pp. 177-87, (2016) (PubMed).
: "Effects of repeated tuberculin skin testings on immune responses in experimental monkeys." in: Journal of animal science and technology, Vol. 56, pp. 32, (2015) (PubMed).
: "IL12p40 regulates functional development of human CD4+ T cells: enlightenment by the elevated expressions of IL12p40 in patients with inflammatory bowel diseases." in: Medicine, Vol. 94, Issue 10, pp. e613, (2015) (PubMed).
: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).
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: "An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2067-2075, (2019) (PubMed).
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- IL-12/IL-23 p40
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别名
- IL12/23 (p40)
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基因ID
- 3592, 3593
抗原
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