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IL-12/IL-23 p40 抗体 (Biotin)

This anti-IL-12/IL-23 p40 antibody is a 小鼠 单克隆 antibody detecting IL-12/IL-23 p40 in ELISA 和 ELISpot. Suitable for 人 和 Non-Human Primate. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN6963861
发货至: 中国

Quick Overview for IL-12/IL-23 p40 抗体 (Biotin) (ABIN6963861)

抗原

IL-12/IL-23 p40

适用

人, Non-Human Primate

宿主

  • 6
  • 2
小鼠

克隆类型

  • 8
单克隆

标记

  • 5
  • 1
  • 1
  • 1
This IL-12/IL-23 p40 antibody is conjugated to Biotin

应用范围

  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, ELISpot

克隆位点

MT618
  • 特异性

    Native and recombinant p40 subunit of IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).

    交叉反应 (详细)

    The monoclonal antibody cross-reacts with IL-12/-23 (p40) from non-human primates.

    产品特性

    This monoclonal antibody enables specific detection of the p40 subunit of human IL-12 and IL-23 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

    纯化方法

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human IL-23

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    ABIN6963861 and ABIN7448304 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAbs .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Masuta, Yamamoto, Natsume-Kitatani, Kanuma, Moriishi, Kobiyama, Mizuguchi, Yasutomi, Ishii: "An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2067-2075, (2019) (PubMed).

    Weinberger, Joos, Reed, Coler, Grubeck-Loebenstein: "The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age." in: Biogerontology, Vol. 17, Issue 1, pp. 177-87, (2016) (PubMed).

    Min, Wang, Yuan, Kuang, Zhao: "Effects of repeated tuberculin skin testings on immune responses in experimental monkeys." in: Journal of animal science and technology, Vol. 56, pp. 32, (2015) (PubMed).

    Wang, Wu, Zhou, Liu, Zhou, Zhu, Song, Zhu, Wang, Xia: "IL12p40 regulates functional development of human CD4+ T cells: enlightenment by the elevated expressions of IL12p40 in patients with inflammatory bowel diseases." in: Medicine, Vol. 94, Issue 10, pp. e613, (2015) (PubMed).

    Gille-Johnson, Smedman, Gudmundsdotter, Somell, Nihlmark, Paulie, Andersson, Gårdlund: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).

  • 抗原

    IL-12/IL-23 p40

    别名

    IL12/23 (p40)

    基因ID

    3592, 3593
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