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TCR beta 抗体

TCR beta 适用: 小鼠 FACS, IP, IF, IHC (fro) 宿主: Armenian Hamster Monoclonal H57-597 unconjugated
产品编号 ABIN6961770
发货至: 中国
  • 抗原 See all TCR beta 抗体
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    适用
    • 29
    • 15
    小鼠
    宿主
    • 21
    • 11
    • 8
    • 4
    Armenian Hamster
    克隆类型
    • 33
    • 11
    单克隆
    标记
    • 12
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    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
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    This TCR beta antibody is un-conjugated
    应用范围
    • 33
    • 11
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
    克隆位点
    H57-597
    亚型
    IgG
    Top Product
    Discover our top product TCR beta Primary Antibody
  • 应用备注
    This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
    说明

    0.5 mg/mL

    限制
    仅限研究用
  • 缓冲液
    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C
    有效期
    12 months
  • 抗原
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    别名
    TCR beta (TCR beta 产品)
    别名
    TCRbeta antibody, Tib antibody, T cell receptor beta chain antibody, Tcrb antibody
    背景
    The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma and delta protein chains, known as the gamma-delta TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can re- sult in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the gamma-delta TCR.
    基因ID
    21577
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