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TCR beta 抗体 (FITC)

TCR beta 适用: 小鼠 FACS, IP, FM 宿主: 仓鼠 Monoclonal H57-597 FITC
产品编号 ABIN6657906
发货至: 中国
  • 抗原 See all TCR beta 抗体
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    适用
    • 29
    • 15
    小鼠
    宿主
    • 22
    • 11
    • 7
    • 4
    仓鼠
    克隆类型
    • 33
    • 11
    单克隆
    标记
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    This TCR beta antibody is conjugated to FITC
    应用范围
    • 33
    • 11
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
    交叉反应 (详细)
    Cross reactivity with TCRbeta from other sources has not been tested
    纯化方法
    Fluorescein conjugated TCRbeta Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse TCRbeta. . Anti-TCRbeta is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC.
    免疫原

    Immunogen: Anti-TCRbeta Antibody (Monoclonal) was produced by repeated immunizations with TCRbeta antigen.

    克隆位点
    H57-597
    亚型
    IgG
    Labeling Ratio
    2-8
    Top Product
    Discover our top product TCR beta Primary Antibody
  • 应用备注

    Application Note: Anti-TCRbeta is useful for Immunofluorescence, Immunoprecipitation, and Flow Cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.

    Immunoprecipitation Dilution: User Optimized

    Flow Cytometry Dilution: 10 μL/10^6 cells (0.1 μg)

    IF Microscopy Dilution: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.1 % Gelatin

    0.09 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.
  • 抗原
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    别名
    TCRbeta (TCR beta 产品)
    别名
    TCRbeta antibody, Tib antibody, T cell receptor beta chain antibody, Tcrb antibody
    背景

    Synonyms: Tib, TCRbeta, T cell receptor beta chain, Tcrb

    Background: The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma and delta protein chains, known as the gamma-delta TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the gamma-delta TCR.

    Gene Name: Tcrb

    基因ID
    21577
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