KLRG1 抗体
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- 抗原 See all KLRG1 抗体
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
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适用
- 小鼠
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宿主
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Golden Syrian Hamster
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克隆类型
- 单克隆
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标记
- This KLRG1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 纯化方法
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
- 克隆位点
- 2F1
- 亚型
- IgG
- Top Product
- Discover our top product KLRG1 Primary Antibody
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anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (FITC)
KLRG1 适用: 小鼠 FACS 宿主: Golden Syrian Hamster Monoclonal 2F1 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 57-119) antibodyKLRG1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 1-189) antibodyKLRG1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 60-195) antibodyKLRG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibodyKLRG1 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 2F1 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (FITC)KLRG1 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 2F1 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (PE)KLRG1 适用: 小鼠 FACS 宿主: Golden Syrian Hamster Monoclonal 2F1 PE
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (APC)KLRG1 适用: 小鼠 FACS 宿主: Golden Syrian Hamster Monoclonal 2F1 APC
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) antibody (violetFluor™ 450)KLRG1 适用: 小鼠 FACS 宿主: Golden Syrian Hamster Monoclonal 2F1 violetFluor™ 450
anti-Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1) (AA 1-189) antibodyKLRG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
- 说明
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0.5 mg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 2-8°C
- 有效期
- 12 months
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- 抗原
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
- 别名
- KLRG1 (KLRG1 产品)
- 别名
- KLRG1 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, 2F1 antibody, CLEC15A antibody, MAFA-2F1 antibody, MAFA-LIKE antibody, killer cell lectin like receptor G1 antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, KLRG1 antibody, Klrg1 antibody
- 背景
- The 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025).The 2F1 antibody may be used as a phenotypic marker for KLRG1 in mouse, frequently in combination with Anti-Mouse CD127 antibody (clone A7R34), for identification of effector T cell populations.
- 基因ID
- 50928
- UniProt
- O88713
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