IL7R 抗体
Quick Overview for IL7R 抗体 (ABIN6961754)
抗原
See all IL7R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
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亚型
- IgG2a kappa
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anti-Interleukin 7 Receptor (IL7R) (AA 173-260) antibody
IL7R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) (AA 21-239) antibodyIL7R 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3F5D9 unconjugated
anti-Interleukin 7 Receptor (IL7R) (AA 21-239) antibodyIL7R 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) (AA 21-236) antibodyIL7R 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal IL7R-2751 unconjugated
anti-Interleukin 7 Receptor (IL7R) (N-Term) antibodyIL7R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) (pTyr449) antibodyIL7R 适用: 人 FACS, WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) antibody (APC)IL7R 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal A7R34 APC
anti-Interleukin 7 Receptor (IL7R) (AA 1-459) antibodyIL7R 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) (Ser552) antibodyIL7R 适用: 人, 小鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 Receptor (IL7R) antibodyIL7R 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
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说明
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0.5 mg/mL
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限制
- 仅限研究用
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缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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有效期
- 12 months
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- IL7R (Interleukin 7 Receptor (IL7R))
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别名
- CD127 (IL-7Ra)
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背景
- The A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells. CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).
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基因ID
- 16172
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UniProt
- P16872
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
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