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FOXP3 抗体 (PE)

This anti-FOXP3 antibody is a 大鼠 单克隆 antibody detecting FOXP3 in FACS. Suitable for 小鼠.
产品编号 ABIN7278292
发货至: 中国

Quick Overview for FOXP3 抗体 (PE) (ABIN7278292)

抗原

See all FOXP3 抗体
FOXP3 (Forkhead Box P3 (FOXP3))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This FOXP3 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MF23
  • 纯化方法

    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

    亚型

    IgG2b
  • 应用备注

    This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system. It is recommended to use the Transcription Factor Staining Buffer Kit (TNB-0607-KIT) for optimal staining results with this antibody.

    说明

    0.2 mg/mL

    限制

    仅限研究用
  • 缓冲液

    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C protected from light

    有效期

    12 months
  • 抗原

    FOXP3 (Forkhead Box P3 (FOXP3))

    别名

    Foxp3

    背景

    The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.

    基因ID

    20371

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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