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H2AFZ 抗体 (acLys4)

This anti-H2AFZ antibody is a 兔 单克隆 antibody detecting H2AFZ in WB, IF, ChIP 和 ChIP-seq. Suitable for 人.
产品编号 ABIN6952410
发货至: 中国

Quick Overview for H2AFZ 抗体 (acLys4) (ABIN6952410)

抗原

See all H2AFZ 抗体
H2AFZ (H2A Histone Family, Member Z (H2AFZ))

适用

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宿主

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克隆类型

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单克隆

标记

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This H2AFZ antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
  • 抗原表位

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    acLys4

    特异性

    Monoclonal antibody raised in rabbit against histone H2A.Z acetylated at Lys4 (H2A.ZK4ac), using a KLH-conjugated synthetic peptide.

    纯化方法

    Protein A purified

    免疫原

    synthetic peptide
  • 应用备注

    ChIP 0.5-1 μg:ChIP
    WB 1:1,000
    IF 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    PBS, 50 % glycerol, 1 % BSA , 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    H2AFZ (H2A Histone Family, Member Z (H2AFZ))

    别名

    H2A.Z

    背景

    Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Acetylation of H2A.ZK4 is associated with gene activation.

    UniProt

    P0C0S5

    途径

    Telomere Maintenance
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