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KDM4A 抗体 (C-Term)

This anti-KDM4A antibody is a 兔 多克隆 antibody detecting KDM4A in WB, IP, ChIP 和 ChIP-seq. Suitable for 人.
产品编号 ABIN6952408
发货至: 中国

Quick Overview for KDM4A 抗体 (C-Term) (ABIN6952408)

抗原

See all KDM4A 抗体
KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

适用

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宿主

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克隆类型

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多克隆

标记

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This KDM4A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

质量等级

ChIP-seq Grade
  • 抗原表位

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    C-Term

    特异性

    Polyclonal antibody raised in rabbit against human JMJD2a (Jumonji domain containing 2a), using a synthetic peptide containing a sequence from the C-terminal part of the protein.

    交叉反应

    小鼠

    纯化方法

    Affinity purified

    免疫原

    synthetic peptide
  • 应用备注

    ChIP 5 μg:ChIP
    WB 1:500
    IP 3 μg:IP

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 μg/μL

    缓冲液

    TBS, 0,1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

    别名

    JMJD2a

    背景

    JMJD2a (UniProtKB/Swiss-Prot entry O75164), belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono- and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.

    UniProt

    O75164

    途径

    Warburg Effect
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