KDM4A 抗体 (C-Term)
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Quick Overview for KDM4A 抗体 (C-Term) (ABIN6952408)
抗原
See all KDM4A 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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特异性
- Polyclonal antibody raised in rabbit against human JMJD2a (Jumonji domain containing 2a), using a synthetic peptide containing a sequence from the C-terminal part of the protein.
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交叉反应
- 小鼠
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纯化方法
- Affinity purified
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免疫原
- synthetic peptide
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应用备注
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ChIP 5 μg:ChIP
WB 1:500
IP 3 μg:IP -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 μg/μL
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缓冲液
- TBS, 0,1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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别名
- JMJD2a
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背景
- JMJD2a (UniProtKB/Swiss-Prot entry O75164), belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono- and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
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UniProt
- O75164
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途径
- Warburg Effect
抗原
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