POLR2A/RPB1 抗体 (pSer5)
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Quick Overview for POLR2A/RPB1 抗体 (pSer5) (ABIN6952400)
抗原
See all POLR2A/RPB1 (POLR2A) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- pSer5
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特异性
- Monoclonal antibody raised in mouse against the YSPTSPS repeat in the B1 subunit of RNA polymerase II, phosphorylated at Ser5 of the repeat sequence.
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纯化方法
- Protein A purified
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亚型
- IgG1
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应用备注
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ChIP/ChIP-seq 1 - 2 μg:ChIP
ELISA 1:3,000
WB 1:1,000
IF 1:500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- PBS, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
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别名
- Pol II
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背景
- RNA polymerase II (pol II) is a key enzyme in the regulation and control of gene transcription. It is able to unwind the DNA double helix, synthesize RNA, and proofread the result. Pol II is a complex enzyme, consisting of 12 subunits, of which the B1 subunit (UniProt/Swiss-Prot entry P24928) is the largest. Together with the second largest subunit, B1 forms the catalytic core of the RNA polymerase II transcription machinery.
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UniProt
- P24928
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途径
- Regulatory RNA Pathways
抗原
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