CBFB 抗体
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北京 101111
Quick Overview for CBFB 抗体 (ABIN6952396)
抗原
See all CBFB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Polyclonal antibody raised in rabbit against human CBFb (core-binding factor, beta subunit) using two KLH-conjugated synthetic peptides containing sequences from the central region of the protein.
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纯化方法
- whole antiserum
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免疫原
- synthetic peptide
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anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-187) antibody
CBFB 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (Internal Region) antibodyCBFB 适用: 人 ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (N-Term) antibodyCBFB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 61-90) antibodyCBFB 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21198 unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) antibodyCBFB 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) antibodyCBFB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 74-163) antibodyCBFB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) antibodyCBFB 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 344C3a unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (N-Term) antibodyCBFB 适用: 人, 斑马鱼, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 85-182) antibodyCBFB 适用: 小鼠 ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ChIP 4 μL:ChIP
ELISA 1:500 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- serum, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CBFB (Core-Binding Factor, beta Subunit (CBFB))
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别名
- CBFb
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背景
- CBFb (UniProtKB/Swiss-Prot entry Q13951) represents the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family. These transcription factors regulate a host of genes specific to haematopoiesis (e.g. RUNX1) and osteogenesis (e.g. RUNX2). The beta subunit is the regulatory subunit which allosterically enhances the activity of the DNA binding alpha subunit as the complex binds to the core site of various enhancers and promoters. CBFb can be involved in a chromosomal rearrangement of chromosome 16 (inv(16)(p13q22)) which produces a fusion protein consisting of the N terminus of CBFb and the C-terminal portion of MYH11. This chromosomal rearrangement is associated with acute myeloid leukaemia of the M4Eo subtype
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UniProt
- Q13951
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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