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HDAC6 抗体 (N-Term)

This anti-HDAC6 antibody is a 兔 多克隆 antibody detecting HDAC6 in ELISA, ChIP 和 ChIP-seq. Suitable for 人.
产品编号 ABIN6952383
发货至: 中国

Quick Overview for HDAC6 抗体 (N-Term) (ABIN6952383)

抗原

See all HDAC6 抗体
HDAC6 (Histone Deacetylase 6 (HDAC6))

适用

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宿主

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克隆类型

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多克隆

标记

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This HDAC6 antibody is un-conjugated

应用范围

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ELISA, Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
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    N-Term

    特异性

    Polyclonal antibody raised in rabbit against human HDAC6 (Histone deacetylase 6), using two KLH-conjugated synthetic peptides from the N-terminal and the central part of the protein, respectively.

    纯化方法

    Peptide affinity purified

    免疫原

    synthetic peptide
  • 应用备注

    ChIP/ChIP-seq 3 μg:ChIP
    ELISA 1:1,000
    WB not recommended

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 μg/μL

    缓冲液

    PBS, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    HDAC6 (Histone Deacetylase 6 (HDAC6))

    别名

    HDAC6

    背景

    HDAC6 (UniProt/Swiss-Prot entry Q9UBN7) belongs to class II of the histone deacetylase family. These enzymes catalyse the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC6 also plays a key role in the degradation of misfolded proteins and in microtubule-dependent cell motility via deacetylation of tubulin and is involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

    UniProt

    Q9UBN7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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