CHD1 抗体 (C-Term)
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Quick Overview for CHD1 抗体 (C-Term) (ABIN6952376)
抗原
See all CHD1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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特异性
- Polyclonal antibody raised in rabbit against human CHD1 (Chromodomain Helicase DNA Binding Protein 1), using a synthetic peptide containing a sequence from the C-terminal part of the protein.
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纯化方法
- Affinity purified
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免疫原
- synthetic peptide
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应用备注
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ChIP 1 μg:ChIP
WB 1:2,000
IP 3 μg:IP -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 μg/μL
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缓冲液
- TBS, 0,1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))
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别名
- CHD1
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背景
- CHD1 (UniProtKB/Swiss-Prot entry O14646) functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. It is required for the recognition of H3K4me3 by the FACT and PAF complexes as well as the U2 snRNP complex and regulates both polymerase II and polymerase I transcription. CHD1 further negatively regulates DNA replication and is required for maintaining open chromatin and pluripotency in embryonic stem cells.
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UniProt
- O14646
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途径
- Chromatin Binding
抗原
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