TGFBR1 抗体
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北京 101111
Quick Overview for TGFBR1 抗体 (ABIN6950907)
抗原
See all TGFBR1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TGF β Receptor I mouse mAb
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特异性
- The antibody can specifically recognize human TGF β Receptor I protein.
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纯化方法
- The antibody was purified by affinity chromatography using a specific immunogen.
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免疫原
- A synthetic peptide corresponding to the amino acid region 34 - 100 of the human TGF beta Receptor I protein.
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亚型
- IgG
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应用备注
- IHC, 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))
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别名
- TGF beta Receptor I
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背景
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Synonyms: AAT5, ALK5, ESS1, LDS1, MSSE, SKR4, TBRI, ALK-5, LDS1A, LDS2A, TBR-i, TGFR-1, ACVRLK4, tbetaR-I, TGF beta Receptor I (TGFBR1)
Background: Members of the transforming growth factor β (TGF-β) superfamily are key regulators of cell proliferation, differentiation, development, morphogenesis, and disease pathogenesis. TGF-β signals through three cell surface receptors: type I (RI), type II (RII), and type III (RIII). Type I and type II receptors are serine/threonine kinases that form heteromeric complexes. Upon ligand binding, type II receptors form a stable complex with type I receptors, leading to phosphorylation and activation of the type I receptor kinase.
Gene Name: TGFBR1 ALK5 SKR4
Protein Name: TGF β Receptor I
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基因ID
- 7046
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UniProt
- P36897
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途径
- Growth Factor Binding
抗原
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