WEE1 抗体 (AA 151-250) (Cy5)
Quick Overview for WEE1 抗体 (AA 151-250) (Cy5) (ABIN6945387)
抗原
See all WEE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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交叉反应
- 人, 大鼠
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预测反应
- Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human WEE1
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亚型
- IgG
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anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer642) antibody
WEE1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 289-388) antibodyWEE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 1-646) antibodyWEE1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 1-646) antibodyWEE1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 适用: 人 IHC (p), DB 宿主: 兔 Polyclonal RB07865 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 604-634) antibodyWEE1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 适用: 人 ELISA, IHC, DB 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 96-130), (Ser123) antibodyWEE1 适用: 人 WB 宿主: 兔 Polyclonal RB57984 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 289-388) antibodyWEE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
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别名
- WEE1
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背景
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Synonyms: DKFZp686I18166, EC 2.7.10.2, FLJ16446, Wee 1, WEE-1, WEE1 protein, Wee1 homolog, WEE1 homolog S. pombe, Wee1 like protein kinase, Wee1 tyrosine kinase, Wee1+ homolog, Wee1+ S. pombe homolog, WEE1A, Wee1A kinase, WEE1hu, WEE1 tyrosine kinase isoform 1, MGC105683, WEE1_HUMAN.
Background: This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
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基因ID
- 7465
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UniProt
- P30291
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
抗原
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