WEE1 抗体 (pSer123)
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- 抗原 See all WEE1 抗体
- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
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抗原表位
- pSer123
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WEE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This phosphorylation site is homologous to Ser123 in Mouse, Rat, and Bovine. The peptide used to produce this antibody has high homology with a sequence occurring in MIER3, and may react with this protein in Mouse and Human when phosphorylated at the site of Ser10.
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human Wee1 around the phosphorylation site of Ser123 [SS(p-S)PV]
- 亚型
- IgG
- Top Product
- Discover our top product WEE1 Primary Antibody
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anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer642) antibody
WEE1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 289-388) antibodyWEE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) antibodyWEE1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 1-646) antibodyWEE1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 1-646) antibodyWEE1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 适用: 人 IHC (p), DB 宿主: 兔 Polyclonal RB07865 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 适用: 人 ELISA, IHC, DB 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 604-634) antibodyWEE1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer642) antibodyWEE1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 96-130), (Ser123) antibodyWEE1 适用: 人 WB 宿主: 兔 Polyclonal RB57984 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
- 别名
- Wee1 (WEE1 产品)
- 别名
- WEE1A antibody, WEE1hu antibody, ATWEE1 antibody, F22D16.3 antibody, F22D16_3 antibody, WEE1 kinase homolog antibody, WEE1-KINASE antibody, WEE1 antibody, Xe-Wee1B antibody, XeWee1B antibody, wee1-b antibody, wee1a antibody, wee2-a antibody, xe-wee1a antibody, xwee1 antibody, wee1 antibody, wee1b antibody, wee1hu antibody, xwee2 antibody, GB19689 antibody, Wee1A antibody, fa20h03 antibody, wu:fa20h03 antibody, zgc:136514 antibody, WEE1 G2 checkpoint kinase antibody, Wee1 kinase antibody, WEE1-like kinase antibody, WEE1 G2 checkpoint kinase S homeolog antibody, wee1 homolog antibody, WEE1 homolog 2 antibody, wee1-like protein kinase antibody, WEE 1 homolog 1 (S. pombe) antibody, M phase inhibitor protein kinase Wee1 antibody, WEE1 antibody, Wee1 antibody, wee1.S antibody, wee1-a antibody, wee2 antibody, LOC551677 antibody, wee1 antibody
- 背景
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Synonyms: WEE1A, WEE1hu, Wee1-like protein kinase, Wee1A kinase, WEE1
Background: Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
- 基因ID
- 7465
- UniProt
- P30291
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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