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UBA2 抗体

This 兔 单克隆 anti-UBA2 antibody (Clone 4F12) specifically detects UBA2 in WB 和 FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6945243
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for UBA2 抗体 (ABIN6945243)

抗原

See all UBA2 抗体
UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

适用

  • 61
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  • 3
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 54
  • 7
  • 1

克隆类型

  • 38
  • 24
单克隆

标记

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  • 3
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  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
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This UBA2 antibody is un-conjugated

应用范围

  • 48
  • 31
  • 25
  • 17
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  • 15
  • 7
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

4F12
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within human UBA2 aa 1-150

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

    别名

    UBA2

    背景

    Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115.

    Background: UBA2 (aka SAE2) functions to induce posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation, which regulates protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins. The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

    基因ID

    10054

    UniProt

    Q9UBT2
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