UBA2 抗体 (AA 1-150)
Our Local Distributor
北京 101111
Quick Overview for UBA2 抗体 (AA 1-150) (ABIN6945243)
抗原
See all UBA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-150
-
原理
- UBA2 (4F12) Monoclonal Antibody
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- Recombinant protein within human UBA2 aa 1-150
-
亚型
- IgG
-
-
-
-
应用备注
- WB(1:300-5000), FCM(1:20-100)
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 12 months
-
-
- UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
-
别名
- UBA2
-
背景
-
Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115.
Background: UBA2 (aka SAE2) functions to induce posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation, which regulates protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins. The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
-
基因ID
- 10054
-
UniProt
- Q9UBT2
抗原
-