TYROBP 抗体
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北京 101111
Quick Overview for TYROBP 抗体 (ABIN6945239)
抗原
See all TYROBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic peptide within human DAP12 aa 60-100.
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亚型
- IgG
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anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (C-Term) antibody
TYROBP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22347 unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 84-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 31-113) antibody (PE)TYROBP 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal PE
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (C-Term) antibodyTYROBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (Cytoplasmic Domain) antibodyTYROBP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113) antibodyTYROBP 适用: 人 WB, FACS, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (Internal Region) antibodyTYROBP 适用: 人 ELISA, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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别名
- TYROBP
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背景
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Synonyms: TYRO protein tyrosine kinase-binding protein, DNAX-activation protein 12, Killer-activating receptor-associated protein, KAR-associated protein, TYROBP, DAP12, KARAP
Background: TYROBP is a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. TYROBP Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.
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基因ID
- 7305
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UniProt
- O43914
抗原
-
