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Tropomyosin 抗体

This 兔 单克隆 anti-Tropomyosin antibody (Clone 2G2) specifically detects Tropomyosin in WB, FACS 和 IHC (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN6945226
发货至: 中国
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Quick Overview for Tropomyosin 抗体 (ABIN6945226)

抗原

See all Tropomyosin (TPM1) 抗体
Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

适用

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人, 大鼠, 小鼠

宿主

  • 56
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克隆类型

  • 37
  • 31
单克隆

标记

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This Tropomyosin antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2G2
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within human Tropomyosin 1 aa 100-300.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

    别名

    Tropomyosin 1

    背景

    Synonyms: Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1, TPM1, C15orf13, TMSA

    Background: Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind Actin filaments and function to modulate Actin-Myosin interaction and stabilize Actin filament structure. Tropomyosin _ is encoded by the TPM1 gene, which maps to human chromosome 15q22.1 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with Actin filaments may increase the rigidity of Actin filaments. Tropomyosin also interacts with Caldesmon to regulate smooth muscle contraction.

    基因ID

    7168

    UniProt

    P09493

    途径

    Regulation of Actin Filament Polymerization
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