Recombinant Transferrin Receptor 抗体 (AA 100-450)
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Quick Overview for Recombinant Transferrin Receptor 抗体 (AA 100-450) (ABIN6945214)
抗原
See all Transferrin Receptor (TFRC) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-450
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原理
- TFRC Recombinant Antibody
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交叉反应
- 人, 大鼠
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预测反应
- Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- Human Transferrin Receptor between 100 to 450 amino acids
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亚型
- IgG
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应用备注
- WB(1:300-5000), Flow-Cyt(1:20-100), ICC/IF(1:50-100)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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别名
- Transferrin Receptor
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背景
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Synonyms: Transferrin receptor protein 1, T9, p90, CD_antigen: CD71, TR, TfR, TfR1, Trfr, TFRC
Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
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UniProt
- P02786
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途径
- Transition Metal Ion Homeostasis
抗原
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