PLAT 抗体 (AA 401-500) (Cy7)
Quick Overview for PLAT 抗体 (AA 401-500) (Cy7) (ABIN6945210)
抗原
See all PLAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 401-500
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交叉反应
 - 小鼠
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预测反应
 - Human,Rat,Dog,Cow,Sheep,Pig
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human Tissue-type plasminogen activator chain B
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亚型
 - IgG
 
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应用备注
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                        IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
 - 12 months
 
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- PLAT (Plasminogen Activator, Tissue (PLAT))
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别名
 - TPA
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背景
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Synonyms: TPA Tissue Plasminogen Activator, Alteplase, DKFZp686I03148, Plasminogen activator tissue, Plasminogen activator tissue type, PLAT, Reteplase, t PA, T Plasminogen Activator, t-PA, T-plasminogen activator, Tissue plasminogen activator (t PA), Tissue type plasminogen activator, Tissue-type plasminogen activator chain B, tPA, TPA_HUMAN, TPA1.
Background: This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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基因ID
 - 5327
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UniProt
 - P00750
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途径
 - Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
 
抗原
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