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STING/TMEM173 抗体

TMEM173 适用: 人 WB, FACS 宿主: 兔 Monoclonal 1B8 unconjugated
产品编号 ABIN6945184
发货至: 中国
  • 抗原 See all STING/TMEM173 (TMEM173) 抗体
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    适用
    • 66
    • 25
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    • 1
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    宿主
    • 80
    • 4
    克隆类型
    • 70
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    单克隆
    标记
    • 40
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    This STING/TMEM173 antibody is un-conjugated
    应用范围
    • 48
    • 28
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    • 18
    • 13
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    • 9
    • 8
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    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within human TMEM173 aa 200 to the C-terminus
    克隆位点
    1B8
    亚型
    IgG
    Top Product
    Discover our top product TMEM173 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    别名
    TMEM173 (TMEM173 产品)
    背景

    Synonyms: Stimulator of interferon genes protein, Endoplasmic reticulum interferon stimulator, Mediator of IRF3 activation, Transmembrane protein 173, hSTING, ERIS, hMITA, TMEM173, ERIS, MITA, STING.

    Background: Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

    基因ID
    340061
    UniProt
    Q86WV6
    途径
    Activation of Innate immune Response
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