THOC1 抗体
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- 抗原 See all THOC1 抗体
- THOC1 (THO Complex 1 (THOC1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This THOC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human Nuclear Matrix Protein p84 aa 300-450
- 克隆位点
- 7G3
- 亚型
- IgG
- Top Product
- Discover our top product THOC1 Primary Antibody
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anti-THO Complex 1 (THOC1) antibody
THOC1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 428-657) antibodyTHOC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyKO Validated THOC1 适用: 人 WB, IF, IP, IHC (p), ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyTHOC1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 428-657) antibodyTHOC1 适用: 人 WB, ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 511-560) antibodyTHOC1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 猴, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyTHOC1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) antibodyTHOC1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 541-570), (C-Term) antibodyTHOC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 540-570), (C-Term) antibodyTHOC1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- THOC1 (THO Complex 1 (THOC1))
- 别名
- THOC1 (THOC1 产品)
- 别名
- p84 antibody, MGC114861 antibody, Tho1 antibody, THOC1 antibody, Hpr1 antibody, HPR1 antibody, P84 antibody, P84N5 antibody, 3110002N20Rik antibody, AW107452 antibody, NMP-84 antibody, LRRGT00070 antibody, THO complex 1 antibody, THO complex 1 protein L homeolog antibody, THO complex subunit 1 antibody, THO complex 1 protein antibody, thoc1 antibody, thoc1.L antibody, THOC1 antibody, LOC100123388 antibody, Thoc1 antibody
- 背景
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Synonyms: THO complex subunit 1, Nuclear matrix protein p84, hTREX84, Tho1, p84N5, THOC1, HPR1.
Background: THOC1 (THO complex subunit 1), also known as Tho1, P84, HPR1 or P84N5, is a 657 amino acid nuclear matrix protein and is evolutionarily conserved from yeast to humans. THOC1 contains one death domain and is a component of the heteromultimeric THO/TREX (transcription/export) complex along with THOC2, THOC3, BAT1 and ALY. The THO/TREX complex is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling elongating Pol II with RNA splicing and export factors. THOC1 is expressed at high levels in breast cancer cells and at relatively low levels in normal epithelia. A reduction of THOC1 in cancer cell lines results in reduced cell proliferation. This suggests that cancer cells are dependent on the high levels of THOC1 expression and therefore THOC1 may be a good target for cancer therapy.
- 基因ID
- 9984
- UniProt
- Q96FV9
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