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Recombinant PICK1 抗体 (N-Term)

This 兔 单克隆 antibody specifically detects PICK1 in WB, IP 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN6944547
发货至: 中国
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Quick Overview for Recombinant PICK1 抗体 (N-Term) (ABIN6944547)

抗原

See all PICK1 抗体
PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

抗体类型

Recombinant Antibody

适用

  • 69
  • 55
  • 43
  • 1
  • 1
人

宿主

  • 68
  • 11
  • 1
兔

克隆类型

  • 53
  • 27
单克隆

标记

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  • 1
  • 1
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This PICK1 antibody is un-conjugated

应用范围

  • 54
  • 30
  • 24
  • 18
  • 13
  • 6
  • 4
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 抗原表位

    • 13
    • 8
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    • 2
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    N-Term

    原理

    PICK1 Recombinant Antibody

    交叉反应

    人

    预测反应

    Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within N-terminal human PICK1.

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), FCM(1:20-100), IP(1-2 μg)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

    别名

    PICK1

    背景

    Synonyms: PRKCA-binding protein, Protein interacting with C kinase 1, protein interacting with PRKCA 1, Protein kinase C-alpha-binding protein, PICK1, PRKCABP

    Background: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

    基因ID

    9463

    UniProt

    Q9NRD5
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