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TCP1 alpha/CCTA 抗体

This anti-TCP1 alpha/CCTA antibody is a 兔 单克隆 antibody detecting TCP1 alpha/CCTA in WB, IHC, FACS, IF (cc) 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6944386
发货至: 中国

Quick Overview for TCP1 alpha/CCTA 抗体 (ABIN6944386)

抗原

See all TCP1 alpha/CCTA (TCP1) 抗体
TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This TCP1 alpha/CCTA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

51A6
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Human p63 between 1 to 250 amino acids

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

    别名

    p63

    背景

    Synonyms: Tumor protein 63, Chronic ulceRative stomatitis protein, KeRatinocyte transcription factor KET, Transformation-related protein 63, Tumor protein p73-like, p40, p51, p63, CUSP, TP63, p73L, TP63

    Background: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.

    基因ID

    8626

    UniProt

    Q9H3D4
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