ORC2 抗体
Quick Overview for ORC2 抗体 (ABIN6944371)
抗原
See all ORC2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Protein G purified monoclonal antibody in PBS containing 0.05% azide.
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免疫原
- Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively
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亚型
- IgG1
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应用备注
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WB 1:300-5000
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 μg/μL
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缓冲液
- PBS with 0.05 % sodium azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
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别名
- ORC2
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背景
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Synonyms: ORC2L, Origin recognition complex subunit 2, ORC2
Background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.
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基因ID
- 4999
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UniProt
- Q13416
抗原
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