ORC2 抗体
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- 抗原 See all ORC2 抗体
- ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ORC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人
- 纯化方法
- Protein G purified monoclonal antibody in PBS containing 0.05% azide.
- 免疫原
- Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively
- 克隆位点
- 5C3
- 亚型
- IgG1
- Top Product
- Discover our top product ORC2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.6 μg/μL
- 缓冲液
- PBS with 0.05 % sodium azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
- 别名
- ORC2 (ORC2 产品)
- 背景
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Synonyms: ORC2L, Origin recognition complex subunit 2, ORC2
Background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.
- 基因ID
- 4999
- UniProt
- Q13416
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