MGEA5 抗体 (N-Term)
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北京 101111
Quick Overview for MGEA5 抗体 (N-Term) (ABIN6944352)
抗原
See all MGEA5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- O-GlcNAcase (1A5) Monoclonal Antibody
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein of N-terminal human MGEA5.
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亚型
- IgG
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应用备注
- WB(1:300-5000), IHC-P(1:200-400), IP(1-2 μg)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
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别名
- OGA
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背景
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Synonyms: Protein O-GlcNAcase, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Meningioma-expressed antigen 5, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase, OGA, NCOAT, MGEA5, HEXC, KIAA0679, MEA5
Background: Isoform 1: - Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro). Does not bind acetyl-CoA and does not have histone acetyltransferase activity. Isoform 3: - Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro), but has about six times lower specific activity than isoform 1.
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基因ID
- 10724
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UniProt
- O60502
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途径
- Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
抗原
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