NMDAR2A 抗体 (pSer1232)
Quick Overview for NMDAR2A 抗体 (pSer1232) (ABIN6944293)
抗原
See all NMDAR2A (GRIN2A) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer1232
-
特异性
- This phosphorylated site is homologous to that of Ser1232 in Mouse and Rat.
-
预测反应
- Human,Mouse,Rat,Pig,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Ser1232
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
-
别名
- NMDAR2A
-
背景
-
Synonyms: NMDAR2A (phospho S1232), p-NMDAR2A (phospho S1232), GRIN2B, Glutamate [NMDA] receptor subunit epsilon 1, Glutamate [NMDA] receptor subunit epsilon 2, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit epsilon-2, GRIN2A, hNR2A, hNR3, N methyl D aspartate receptor subtype 2A, N methyl D aspartate receptor subtype 2B, N-methyl D-aspartate receptor subtype 2A, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDAR2A, NMDAR2B, NMDE2_HUMAN, NR2A, NR2B, NR3.
Background: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
-
基因ID
- 2903
-
UniProt
- Q12879
-
途径
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-