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NMDAR2A 抗体 (pSer1232)

This anti-NMDAR2A antibody is a 兔 多克隆 antibody detecting NMDAR2A in ELISA, ICC, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN6944293
发货至: 中国

Quick Overview for NMDAR2A 抗体 (pSer1232) (ABIN6944293)

抗原

See all NMDAR2A (GRIN2A) 抗体
NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

适用

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宿主

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克隆类型

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多克隆

标记

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This NMDAR2A antibody is un-conjugated

应用范围

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ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    pSer1232

    特异性

    This phosphorylated site is homologous to that of Ser1232 in Mouse and Rat.

    预测反应

    Human,Mouse,Rat,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Ser1232

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

    别名

    NMDAR2A

    背景

    Synonyms: NMDAR2A (phospho S1232), p-NMDAR2A (phospho S1232), GRIN2B, Glutamate [NMDA] receptor subunit epsilon 1, Glutamate [NMDA] receptor subunit epsilon 2, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit epsilon-2, GRIN2A, hNR2A, hNR3, N methyl D aspartate receptor subtype 2A, N methyl D aspartate receptor subtype 2B, N-methyl D-aspartate receptor subtype 2A, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDAR2A, NMDAR2B, NMDE2_HUMAN, NR2A, NR2B, NR3.

    Background: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

    基因ID

    2903

    UniProt

    Q12879

    途径

    Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
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