NMDAR2A 抗体 (AA 23-165)
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Quick Overview for NMDAR2A 抗体 (AA 23-165) (ABIN5611284)
抗原
See all NMDAR2A (GRIN2A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 23-165
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原理
- GRIN2A Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human GRIN2A (AA: 23-165) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
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别名
- GRIN2A
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背景
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This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
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分子量
- 165.3 kDa
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UniProt
- Q12879
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途径
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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