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MMP13 抗体

This anti-MMP13 antibody is a 兔 单克隆 antibody detecting MMP13 in WB, IHC, IHC (p), IF (cc) 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN6944105
发货至: 中国

Quick Overview for MMP13 抗体 (ABIN6944105)

抗原

See all MMP13 抗体
MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

适用

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人, 小鼠

宿主

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克隆类型

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单克隆

标记

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This MMP13 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

克隆位点

4C4
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    N terminus human MMP13

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

    别名

    MMP13

    背景

    Synonyms: Collagenase 3, Matrix metalloproteinase-13, MMP-13, MMP13

    Background: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

    基因ID

    4322

    UniProt

    P45452
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