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MMP13 抗体 (N-Term)

MMP13 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263293
发货至: 中国
  • 抗原 See all MMP13 抗体
    MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
    抗原表位
    • 15
    • 15
    • 8
    • 8
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    • 7
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    N-Term
    适用
    • 110
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    • 3
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 119
    • 13
    • 7
    克隆类型
    • 121
    • 18
    多克隆
    标记
    • 63
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    • 3
    • 3
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    This MMP13 antibody is un-conjugated
    应用范围
    • 116
    • 59
    • 47
    • 27
    • 26
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    • 22
    • 15
    • 14
    • 9
    • 8
    • 3
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    MMP13 Antibody detects endogenous levels of total MMP13.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MMP13, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MMP13 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
    别名
    MMP13 (MMP13 产品)
    别名
    CLG3 antibody, MANDP1 antibody, Clg antibody, MMP-13 antibody, Mmp1 antibody, cb1034 antibody, mmp13 antibody, gene A antibody, xCol antibody, xcl3 antibody, MMP13 antibody, MGC108008 antibody, matrix metallopeptidase 13 antibody, matrix metallopeptidase 13a antibody, matrix metallopeptidase 13 (collagenase 3) like S homeolog antibody, matrix metallopeptidase 13 (collagenase 3) antibody, matrix metalloproteinase 13 antibody, matrix metallopeptidase 13 (collagenase 3) like L homeolog antibody, MMP13 antibody, Mmp13 antibody, mmp13a antibody, mmp13l.S antibody, mmp13 antibody, LOC100136348 antibody, mmp13l.L antibody
    背景

    Description: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

    Gene: MMP13

    分子量
    54kDa
    基因ID
    4322
    UniProt
    P45452
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