MECP2 抗体
Quick Overview for MECP2 抗体 (ABIN6944061)
抗原
See all MECP2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
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免疫原
- Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
dot-blot() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.2 μg/μL
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缓冲液
- PBS with 0.05 % sodium azide and 0.05 % Proclin300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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别名
- MeCP2
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背景
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Synonyms: Methyl-CpG-binding protein 2, MECP2, MeCp-2 protein
Background: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
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基因ID
- 4204
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UniProt
- P51608
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途径
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
抗原
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