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LIG4 抗体

LIG4 适用: 人 WB, IHC (p) 宿主: 兔 Monoclonal 2D9 unconjugated
产品编号 ABIN6943923
发货至: 中国
  • 抗原 See all LIG4 抗体
    LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
    适用
    • 60
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    宿主
    • 58
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    克隆类型
    • 51
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    单克隆
    标记
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    This LIG4 antibody is un-conjugated
    应用范围
    • 33
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    • 9
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    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within human DNA Ligase IV aa 500-700
    克隆位点
    2D9
    亚型
    IgG
    Top Product
    Discover our top product LIG4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
    别名
    LIG4 (LIG4 产品)
    别名
    zgc:165595 antibody, lig4 antibody, DNA LIGASE IV antibody, LIG4 antibody, lig4-A antibody, 5830471N16Rik antibody, tiny antibody, DNL4 antibody, ligase IV, DNA, ATP-dependent antibody, DNA ligase 4 antibody, ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining antibody, DNA ligase IV antibody, ligase IV, DNA, ATP-dependent L homeolog antibody, lig4 antibody, LIG4 antibody, LOC100212302 antibody, CpipJ_CPIJ005161 antibody, PTRG_09982 antibody, MCYG_05151 antibody, LOC657210 antibody, ATLIG4 antibody, lig4.L antibody, Lig4 antibody
    背景

    Synonyms: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4.

    Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

    基因ID
    3981
    UniProt
    P49917
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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