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LIG4 抗体

This anti-LIG4 antibody is a 兔 单克隆 antibody detecting LIG4 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN6943923
发货至: 中国

Quick Overview for LIG4 抗体 (ABIN6943923)

抗原

See all LIG4 抗体
LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

适用

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宿主

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克隆类型

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单克隆

标记

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This LIG4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2D9
  • 交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within human DNA Ligase IV aa 500-700

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

    别名

    LIG4

    背景

    Synonyms: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4.

    Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

    基因ID

    3981

    UniProt

    P49917

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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