Recombinant LIG4 抗体 (AA 500-700)
Our Local Distributor
北京 101111
Quick Overview for Recombinant LIG4 抗体 (AA 500-700) (ABIN6943923)
抗原
See all LIG4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 500-700
-
原理
- DNA Ligase IV Recombinant Antibody
-
交叉反应
- 人
-
纯化方法
- Purified by Protein A.
-
免疫原
- Recombinant protein within human DNA Ligase IV aa 500-700
-
亚型
- IgG
-
-
-
-
应用备注
- WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(), ICC/IF(1:50-100)
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
-
别名
- LIG4
-
背景
-
Synonyms: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4.
Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
-
基因ID
- 3981
-
UniProt
- P49917
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-