Recombinant LGALS8 抗体 (AA 1-100)
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北京 101111
Quick Overview for Recombinant LGALS8 抗体 (AA 1-100) (ABIN6943917)
抗原
See all LGALS8 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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原理
- Galectin 8 Recombinant Antibody
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic peptide within human Galectin 8 aa 1-100
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亚型
- IgG
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应用备注
- Flow-Cyt(1:50-100), ICC/IF(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))
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别名
- LGALS8
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背景
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Synonyms: Galectin-8, Po66 carbohydrate-binding protein, Prostate carcinoma tumor antigen 1, Gal-8, Po66-CBP, PCTA-1, LGALS8
Background: Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane, these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.
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基因ID
- 3964
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UniProt
- O00214
抗原
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