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IKZF1 抗体 (AA 250-450)

The 兔 单克隆 anti-IKZF1 antibody (Clone 5D4) (ABIN6943787) specifically detects IKZF1 in WB, FACS 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN6943787
发货至: 中国
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Quick Overview for IKZF1 抗体 (AA 250-450) (ABIN6943787)

抗原

See all IKZF1 抗体
IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

适用

  • 116
  • 52
  • 45
  • 5
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  • 4
  • 4
  • 4
  • 1
  • 1
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宿主

  • 90
  • 25
  • 2

克隆类型

  • 69
  • 48
单克隆

标记

  • 45
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  • 1
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This IKZF1 antibody is un-conjugated

应用范围

  • 83
  • 46
  • 42
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  • 13
  • 13
  • 9
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  • 5
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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

5D4
  • 抗原表位

    • 36
    • 15
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-450

    原理

    IKZF1 (5D4) Monoclonal Antibody

    交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within human Ikaros aa 250-450

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

    别名

    IKZF1

    背景

    Synonyms: DNA-binding protein Ikaros, Ikaros family zinc finger protein 1, Lymphoid transcription factor LyF-1, IKZF1, IK1, IKAROS, LYF1, ZNFN1A1

    Background: Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs). Function is isoform-specific and is modulated by dominant-negative inactive isoforms

    基因ID

    10320

    UniProt

    Q13422

    途径

    Production of Molecular Mediator of Immune Response
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