HSPE1 抗体
Quick Overview for HSPE1 抗体 (ABIN6943761)
抗原
See all HSPE1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human Cpn10 aa 1-150.
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IP(1-2 μg) -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))
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别名
- HSPE1
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背景
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Synonyms: 10 kDa heat shock protein mitochondrial, 10 kDa chaperonin, Chaperonin 10, Early-pregnancy factor, Hsp10, CPN10, EPF, HSPE1
Background: Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable)
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基因ID
- 3336
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UniProt
- P61604
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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