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HDAC9 抗体

This anti-HDAC9 antibody is a 兔 单克隆 antibody detecting HDAC9 in WB, IHC (p), FACS, IF (cc) 和 IF (p). Suitable for 人 和 大鼠.
产品编号 ABIN6943611
发货至: 中国

Quick Overview for HDAC9 抗体 (ABIN6943611)

抗原

See all HDAC9 抗体
HDAC9 (Histone Deacetylase 9 (HDAC9))

适用

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人, 大鼠

宿主

  • 70
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克隆类型

  • 62
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单克隆

标记

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This HDAC9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

克隆位点

2C9
  • 交叉反应

    人, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within human HDAC9 aa 1-150

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    HDAC9 (Histone Deacetylase 9 (HDAC9))

    别名

    HDAC9

    背景

    Synonyms: Histone deacetylase 9, Histone deacetylase 7B, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, HD9, HD7, HD7b, HDAC9, HDAC7, HDAC7B, HDRP, KIAA0744, MITR.

    Background: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is a critical component of transcriptional regulation and the acetylation of nucleosomal histones is a major source of this remodeling. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Several mammalian proteins function as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Conversely, the deacetylation of histones is associated with transcriptional silencing. The histone deacetylases (HDAC) include HDAC1-9. HDAC9 and HDAC9a are two alternatively spliced isoforms of HDAC9. HDAC9a is 132 amino acids shorter than HDAC9, but both isoforms contain the HDAC catalytic domain, remain capable of deacetylase activity and repress myoctye enhancer-binding factor 2-mediated transcription.

    基因ID

    9734

    UniProt

    Q9UKV0

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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